Luís A. Nunes Amaral
Professor of Engineering Sciences and Applied Mathematics
Professor of Medicine (by courtesy)
Professor of Molecular Biosciences (by courtesy)
Professor of Physics & Astronomy (by courtesy)
Chemical & Biological Engineering
2145 Sheridan Road (Room E136)
Evanston, IL 60208, US
Phone:
(847) 491-7850Scale invariance in the nonstationarity of human heart rate
Physical Review Letters 87, 168105 (2001)
Times cited: 87
Abstract
We introduce a segmentation algorithm to probe the temporal organization of heterogeneities in human heartbeat interval time series. We find that the lengths of segments with different local mean heart rates follow a power-law distribution and show that this scale-invariant structure is not a simple consequence of the long-range correlations present in the data. The differences in mean heart rates between consecutive segments display a common functional form, but with different parameters for healthy individuals and for heart-failure patients. These findings suggest that there is relevant physiological information hidden in the heterogeneities of the heartbeat time series.